1 ms single-pulse monopolar electrical stimulation constant-current digitimer ds7 Search Results


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<t> Stimulation </t> conditions and parameters
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<t> Stimulation </t> conditions and parameters
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Image Search Results


 Stimulation  conditions and parameters

Journal: The Journal of Neuroscience

Article Title: Alpha-Band Brain Oscillations Shape the Processing of Perceptible as well as Imperceptible Somatosensory Stimuli during Selective Attention

doi: 10.1523/JNEUROSCI.2582-16.2017

Figure Lengend Snippet: Stimulation conditions and parameters

Article Snippet: Electrical finger nerve stimulation was performed by constant-current stimulators (DS7A, Digitimer) applying single current square wave pulses (duration 200 μs), controlled by the stimulation software “Presentation” (Neurobehavioral Systems).

Techniques: Blocking Assay

Experimental setup and stimulation paradigm. Forty subjects received 936 imperceptible electrical pulses to the left index finger via the DS7A (Digitimer) over 26 two-minute blocks. In each block, up to four perceptible stimuli were randomly presented to the left or right hand (in total 104). Absolute detection thresholds were determined initially using the method of limits (one ascending trial) and a subsequent yes/no adaptive detection task consisting of 30–60 trials (maximally 5 min, including blank/ catch trials) and subsequently every four measurement blocks.

Journal: The Journal of Neuroscience

Article Title: Alpha-Band Brain Oscillations Shape the Processing of Perceptible as well as Imperceptible Somatosensory Stimuli during Selective Attention

doi: 10.1523/JNEUROSCI.2582-16.2017

Figure Lengend Snippet: Experimental setup and stimulation paradigm. Forty subjects received 936 imperceptible electrical pulses to the left index finger via the DS7A (Digitimer) over 26 two-minute blocks. In each block, up to four perceptible stimuli were randomly presented to the left or right hand (in total 104). Absolute detection thresholds were determined initially using the method of limits (one ascending trial) and a subsequent yes/no adaptive detection task consisting of 30–60 trials (maximally 5 min, including blank/ catch trials) and subsequently every four measurement blocks.

Article Snippet: Electrical finger nerve stimulation was performed by constant-current stimulators (DS7A, Digitimer) applying single current square wave pulses (duration 200 μs), controlled by the stimulation software “Presentation” (Neurobehavioral Systems).

Techniques: Blocking Assay

Boxplots depict individually averaged d-prime values across the sample for the seven different stimulation intensity categories of our psychophysics control experiment showing that participants are zero sensitive to stimulation intensities below the individually adjusted absTH. Absolute detection threshold served as individual reference for decreasing subTH stimulation intensities ∼15% or 30%. NTH intensities were tuned to 25%, 50%, or 75% of the distance between absolute detection threshold and 100% STH. Raw hit and false alarm rates were corrected according to Hautus (1995) to account for extreme values (i.e., no responses to target or catch trials). Notches indicate 95% confidence intervals.

Journal: The Journal of Neuroscience

Article Title: Alpha-Band Brain Oscillations Shape the Processing of Perceptible as well as Imperceptible Somatosensory Stimuli during Selective Attention

doi: 10.1523/JNEUROSCI.2582-16.2017

Figure Lengend Snippet: Boxplots depict individually averaged d-prime values across the sample for the seven different stimulation intensity categories of our psychophysics control experiment showing that participants are zero sensitive to stimulation intensities below the individually adjusted absTH. Absolute detection threshold served as individual reference for decreasing subTH stimulation intensities ∼15% or 30%. NTH intensities were tuned to 25%, 50%, or 75% of the distance between absolute detection threshold and 100% STH. Raw hit and false alarm rates were corrected according to Hautus (1995) to account for extreme values (i.e., no responses to target or catch trials). Notches indicate 95% confidence intervals.

Article Snippet: Electrical finger nerve stimulation was performed by constant-current stimulators (DS7A, Digitimer) applying single current square wave pulses (duration 200 μs), controlled by the stimulation software “Presentation” (Neurobehavioral Systems).

Techniques: Control

Subthreshold (A) and suprathreshold (B) isocontour voltage maps and SEPs. Aa, Average voltage topographies for a window of 50–60 ms poststimulus (grand average, GAVG, n = 37 participants) for the subthreshold left attended condition on the left and topographical p value distribution on the right side (t tests against baseline −100 to −20 ms prestimulus, fdr-corrected). Nonsignificant electrodes (p > 0.05) are masked in dark blue, significant electrodes are emphasized by large purple discs in the voltage plot. Ab, Grand average SEPs at channel CP4 for the subthreshold left attended condition. The bottom plot shows the SEPs on a zoomed scale for the yellow shaded area of the top plot. Time is expressed relative to stimulus onset (0 ms). Lightly shaded background areas indicate 95% confidence intervals derived from paired t tests of each data point against mean baseline activity. Ac, Ba, and Bc are the same as Aa but for the subthreshold left unattended, suprathreshold left attended and suprathreshold left unattended conditions, respectively. Note the different scaling of the ordinate for suprathreshold stimulation. Ad is the same as Ab but for the subthreshold left unattended condition. Bb and Bd are the same as Ab and Ad but for the suprathreshold left attended and suprathreshold left unattended conditions, respectively. Note the different scaling of the ordinate.

Journal: The Journal of Neuroscience

Article Title: Alpha-Band Brain Oscillations Shape the Processing of Perceptible as well as Imperceptible Somatosensory Stimuli during Selective Attention

doi: 10.1523/JNEUROSCI.2582-16.2017

Figure Lengend Snippet: Subthreshold (A) and suprathreshold (B) isocontour voltage maps and SEPs. Aa, Average voltage topographies for a window of 50–60 ms poststimulus (grand average, GAVG, n = 37 participants) for the subthreshold left attended condition on the left and topographical p value distribution on the right side (t tests against baseline −100 to −20 ms prestimulus, fdr-corrected). Nonsignificant electrodes (p > 0.05) are masked in dark blue, significant electrodes are emphasized by large purple discs in the voltage plot. Ab, Grand average SEPs at channel CP4 for the subthreshold left attended condition. The bottom plot shows the SEPs on a zoomed scale for the yellow shaded area of the top plot. Time is expressed relative to stimulus onset (0 ms). Lightly shaded background areas indicate 95% confidence intervals derived from paired t tests of each data point against mean baseline activity. Ac, Ba, and Bc are the same as Aa but for the subthreshold left unattended, suprathreshold left attended and suprathreshold left unattended conditions, respectively. Note the different scaling of the ordinate for suprathreshold stimulation. Ad is the same as Ab but for the subthreshold left unattended condition. Bb and Bd are the same as Ab and Ad but for the suprathreshold left attended and suprathreshold left unattended conditions, respectively. Note the different scaling of the ordinate.

Article Snippet: Electrical finger nerve stimulation was performed by constant-current stimulators (DS7A, Digitimer) applying single current square wave pulses (duration 200 μs), controlled by the stimulation software “Presentation” (Neurobehavioral Systems).

Techniques: Derivative Assay, Activity Assay

Subthreshold stimulation increases, suprathreshold stimulation decreases Rolandic rhythms. Grand average time frequency plots (contralateral to stimulation side at CP4) for subthreshold (Aa and Ab) and suprathreshold (Ba and Bb) stimulation after selection and forward projection of pericentral independent mu components. Time is expressed relative to stimulation onset, oscillatory activity is expressed relative to baseline amplitude (baseline: −700 to −200 ms prestimulus). Light colored areas did not survive fdr-correction for multiple comparisons at q = 0.05 (Genovese et al., 2002).

Journal: The Journal of Neuroscience

Article Title: Alpha-Band Brain Oscillations Shape the Processing of Perceptible as well as Imperceptible Somatosensory Stimuli during Selective Attention

doi: 10.1523/JNEUROSCI.2582-16.2017

Figure Lengend Snippet: Subthreshold stimulation increases, suprathreshold stimulation decreases Rolandic rhythms. Grand average time frequency plots (contralateral to stimulation side at CP4) for subthreshold (Aa and Ab) and suprathreshold (Ba and Bb) stimulation after selection and forward projection of pericentral independent mu components. Time is expressed relative to stimulation onset, oscillatory activity is expressed relative to baseline amplitude (baseline: −700 to −200 ms prestimulus). Light colored areas did not survive fdr-correction for multiple comparisons at q = 0.05 (Genovese et al., 2002).

Article Snippet: Electrical finger nerve stimulation was performed by constant-current stimulators (DS7A, Digitimer) applying single current square wave pulses (duration 200 μs), controlled by the stimulation software “Presentation” (Neurobehavioral Systems).

Techniques: Selection, Activity Assay

For all subplots, blue and red bars depict the attended and unattended conditions, respectively. A, Subthreshold (left) and suprathreshold (right) SEPs and (B) grand-average attention effect for prestimulus mu amplitude (−1000 to −200 ms). Error bars indicate 95% confidence intervals of the mean. Asterisks indicate significance at p < 0.05. C, Subthreshold stimulation: relationship between prestimulus mu and SEP amplitudes (Ca) and prestimulus mu amplitude values averaged across trials within each bin (−300 to −200 ms; Cb). D, Suprathreshold stimulation: same as C but for the suprathreshold left attended condition. Da, Additionally, red dots show the average hit rates for each mu amplitude bin and the red solid line depicts the fit of the LMM for the suprathreshold left attended condition. Overlaid dashed and dotted lines in Ca and Da are fits of the LMM for respective SEP amplitudes. Red dots (with 95% confidence intervals) in Cb and Db depict the difference in absolute number of trials of each mu amplitude bin between attention conditions.

Journal: The Journal of Neuroscience

Article Title: Alpha-Band Brain Oscillations Shape the Processing of Perceptible as well as Imperceptible Somatosensory Stimuli during Selective Attention

doi: 10.1523/JNEUROSCI.2582-16.2017

Figure Lengend Snippet: For all subplots, blue and red bars depict the attended and unattended conditions, respectively. A, Subthreshold (left) and suprathreshold (right) SEPs and (B) grand-average attention effect for prestimulus mu amplitude (−1000 to −200 ms). Error bars indicate 95% confidence intervals of the mean. Asterisks indicate significance at p < 0.05. C, Subthreshold stimulation: relationship between prestimulus mu and SEP amplitudes (Ca) and prestimulus mu amplitude values averaged across trials within each bin (−300 to −200 ms; Cb). D, Suprathreshold stimulation: same as C but for the suprathreshold left attended condition. Da, Additionally, red dots show the average hit rates for each mu amplitude bin and the red solid line depicts the fit of the LMM for the suprathreshold left attended condition. Overlaid dashed and dotted lines in Ca and Da are fits of the LMM for respective SEP amplitudes. Red dots (with 95% confidence intervals) in Cb and Db depict the difference in absolute number of trials of each mu amplitude bin between attention conditions.

Article Snippet: Electrical finger nerve stimulation was performed by constant-current stimulators (DS7A, Digitimer) applying single current square wave pulses (duration 200 μs), controlled by the stimulation software “Presentation” (Neurobehavioral Systems).

Techniques: